| Date | Home | Away | Result |
|---|---|---|---|
| 12/03/26 17:45 | Panathinaikos Athens | Real Betis Sevilla | 1-0 |
| 12/03/26 17:45 | FC Bologna | AS Roma | 1-1 |
| 12/03/26 17:45 | VfB Stuttgart | FC Porto | 1-2 |
| 12/03/26 17:45 | OSC Lille | Aston Villa | 0-1 |
| 12/03/26 20:00 | Celta Vigo | Olympique Lyon | 1-1 |
| 12/03/26 20:00 | KRC Genk | SC Freiburg | 1-0 |
| 12/03/26 20:00 | Ferencvaros Budapest | Sporting Braga | 2-0 |
| 12/03/26 20:00 | Nottingham Forest | FC Midtjylland | 0-1 |